Claudio Coello 22 is a five-floor mixed use commercial property in Madrid, Spain. This building has approximately 37,000 square feet and on-site parking spaces. It has retail, office, and residential components along with an open courtyard.

It is located in the Barrio de Salamanca neighborhood, the most exclusive and expensive area in Madrid. Barrio de Salamanca is a central location in the city and is home to the headquarters of several major banks and law firms. It also is the site of prominent high-end retail.

This property is also located less than a block from the National Archaeological Museum and Biblioteca Nacional de Espana.

Claudio Coello 22 was developed by an affiliate company of Key International in 1994.